Tuesday, October 18, 2011

PFO stroke trials will continu

Closure of foramen ovale (PFO) closed and the CLOSURE of/TIA stroke prevention I test early data shows that trial did not meet Primary endpoint.   This also led to some speculation that other similar test will have the same problem, would abort their test? 2 of the major test in the test is to REDUCE and RESPECT test.   2 companies were responsible for the test to confirm that they do not interrupt test intentions.   CLOSURE I all test results are expected to be published in November 2010 in United States society of Cardiology's annual meeting.   REDUCE test in the United States and the United Kingdom and Scandinavia 664 cases into groups, random 2:1 to operate closed or medication, is scheduled for completion in 2014 will all of the data. RESPECT trial in the United States 55 centres into group 710 patients, this trial has completed the initial test data to study primary endpoint is the prevention of recurrent stroke. www.cmt.com.cn  

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